Regular Article CLINICAL TRIALS AND OBSERVATIONS Stem cell transplantation can provide durable disease control in blastic plasmacytoid dendritic cell neoplasm: a retrospective study from the European Group for Blood and Marrow Transplantation
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چکیده
*Damien Roos-Weil,1 *Sascha Dietrich,2,3 Ariane Boumendil,3 Emmanuelle Polge,4 Dominique Bron,5 Enric Carreras,6 Arturo Iriondo Atienza,7 William Arcese,8 Dietrich W. Beelen,9 Jan J. Cornelissen,10 Nicolaus Kröger,11 Giuseppe Milone,12 Giuseppe Rossi,13 Fabrice Jardin,14 Christina Peters,15 Vanderson Rocha,16 Anna Sureda,17 Mohamad Mohty,18 and Peter Dreger,2,3 on behalf of the European Group for Blood and Marrow Transplantation Lymphoma, Pediatric Diseases, and Acute Leukemia Working Parties
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We analyzed the outcomes of 74 patients diagnosed with BCR-ABL myeloproliferative neoplasms in blast phase receiving induction chemotherapy (55%), low-intensity therapy (16%), stem cell transplantation (SCT; 3%), or supportive care (26%). Median survival from the date of blastic transformation was 5 months. Patients receiving supportive therapy had a median survival of 6 weeks. Complete remissi...
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1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; 2Blood and Marrow Transplant Clinical Trials Network, Rockville, MD; 3Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA; 4University of Michigan Medical Center, Ann Arbor; 5EMMES Corporation, Rockville, MD; and 6The Center for International Blood and Marrow Transplant Researc...
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1Department of Pediatrics and Bone Marrow Transplant Unit, University Hospital Schleswig-Holstein, Kiel, Germany; 2LWP Statistician, Research Institute, Hospital de la Sant Pau, Barcelona, Spain; 3Department of Hematology, University Hospital Gasthuisberg, Leuven, Belgium; 4Bone Marrow Transplant Unit, Schneider Children’s Medical Center of Israel, Petach-Tikva, Israel; 5Department of Pediatric...
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This study reports outcomes of allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning (RIC) in 186 patients with chronic myeloid leukemia (CML) from the European Group for Blood and Marrow Transplantation (EBMT). The median age was 50 years, and 64% were in first chronic phase (CP1), CP2 13%, accelerated phase 17%, and blast crises 6%. The median EBMT transplant ...
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